- Leishmaniasis is a disease caused by Leishmania donovani.
- It has two hosts. Man is the primary host and sandfly is the secondary or intermediate host.
- When a sandfly bites an infected man, it takes amastigote form of Leishmania from the blood of the man.
- Then the parasites enter the midgut of the sandfly.
- In the midgut, the parasites change into promastigote form.
- Then they reproduce by means of longitudinal binary fission.
- When the number of parasites is enormous, they come to the buccal cavity and pharynx of the sandfly.
- When an infected sandfly bites a man, the parasites transferred into the man’s body from the buccal cavity of the sandfly.
- This is the way how sandflies cause Leishmaniasis.
Read life cycle of Leishmania donovani to know in details.